Faculty and Staff
Anthony W. Wren
Assist Professor Biomaterials
Alfred University Contact Info
Office Location: Binns Merrill 217
Department: Matls Science & Engineering  
Office Hours: Mon: 2-4
Tue: 2-4
Wed: 2-4

 
Phone: 607.871.2183  
Email:    
Anthony W. Wren
Education
PhD.: Biomedical Materials - Bioactive Bone Cements
University of Limerick, Ireland, 2008

M.Sc.: Biomedical Engineering - Diagnostic Medical Divices
University of Limerick, Ireland, 2005

B.Sc.: Science - Biology, Exp. Physics, Math. Physics, Mathematics
National University of Ireland, Maynooth, Ireland, 2003

Background
Activities
My primary research interests include designing and characterizing novel glasses for use as medical devices. Principal analytical techniques for glass design include X-ray Diffraction (XRD), X-ray Photoelectron Spectroscopy (XPS) and Raman Spectroscopy. Further interests include quantifying ion release from bioactive glasses/materials and their effect on common skin microflorasuch as bacteria (E. coli, S. epidermidis, S. aureus, P. aeruginosa) and yeast (candida albicans) responsible for infection. My research interests also include cytotoxicity testing of biomaterials on mammalian (Mouse L929 Fibroblasts) cells, with the intention to commence testing on both bone and cancer cell lines in the near future. My current research projects include:

• Fabrication of Glass/Ceramic Cell Scaffolds for increased bioactivity.

• Glass Coatings to increase the antimicrobial response and their subsequent diffusion through soluble and stable Hydrogels/Gels for applications in wound healing.

• Bone Cements based on Glass Polyalkenoate Cement chemistry for load bearing applications.

• Anti-cancerous Bone Cements and Degradable Bioactive Glasses.



Post-Doctoral Education

2008-2011 Univerisity of Limerick/Alfred University

Post-Doctoral studies was undertaken between the University of LImerick, Ireland and Alfred University , NY.

Research projects are as mentioned above.



Professional Affiliations

European Society of Biomaterials (ESB)

Society of Biomaterials (SOB)

American Ceramics Society (ACers)

American Society for Engineering Education (ASEE)



Classes Taught

CEMS - 465 Biocompatibility

CEMS - 334 Introduction to Polymers

ENGR - 111 Explorations in Biomaterials

BIOL - 202 Adjunct Instructor in Biology Labs



Links of Interest

http://scholes.alfred.edu/

http://herrick.alfred.edu/



Selected Publications

1) Fabrication of CaO-NaO-SiO2/TiO2 scaffolds for surgical applications.A.W. Wren, A. Coughlan, K.E. Smale, S.T. Misture, B.P. Mahon, O.M. Clarkin, M.R. Towler. J. Mat. Sci: Mater. Med. DOI: 10.1007/s10856-012-4746-8 2012.

2) Gallium containing glass polyalkenoate anti-cancerous bone cements:glass characterization and physical properties. J. Mat. Sci: Mater. Med. 23 : 8 1823-1833 2012.

3) Silver coated bioactive glass particles for wound healing applications. A.W. Wren, A. Coughlan, P. Hassanzadeh, M.R. Towler. J. Mat. Sci: Mater. Med. 23: 5 1331-1341 2012.

4) The Structural Role of Titanium in Ca-Sr-Zn-Si/Ti Glasses for Medical Applications. A.W. Wren, A. Kidari, F.R. Laffir, M.R. Towler. J Non-Crys. Solids. 357: 3 1021-1026 2011.

5) The Bioactivity and Ion Release of Titanium-Containing Glass Polyalkenoate Cements for Medical Applications. A.W. Wren, N.M. Cummins, F.R. Laffir, S.P. Hudson, M.R. Towler. J. Mat. Sci: Mater. Med. 22: 19-28 2011.

6) Solgel derived silver incorporated titania thin films on glass: bactericidal and photocatalytic activity. B.A. Akgun, A.W. Wren, C. Durucan, M.R. Towler, N.P. Mellott, J. Sol-Gel Sci. 59: 2 228-238 2011.

Full Listing see Vitae



Current Research

1) Dextran hydrogels as carriers for bioactive glasses. delivery of Gallium containing glasses for anti-tumor effects.

2) The effect of thermal treatment on the rheological and mechanical properties and bioactivity of Ti-glass polyalkenoate cemnts.

3) Sr-doped hydroxyapatite modified with bioactive glass, properties and bioactive effects.

4) The effect of alternating Na and Sr concentration on the structure of glass-ceramic scaffolds.

Vitae Document
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