Rahman Monzur

Visiting Assistant Professor of Biology
College Liberal Arts/Sciences

Education

  • Ph.D., Molecular Biology, Okayama University, 1997
  • M.Sc., University of Dhaka, 1992

Specialties / Areas of Interest

  • Cell signaling
  • Microbial pathogenicity

Biography

Research Interest

The existence of life is a fine-tune between growth and death specifically at the cellular and molecular levels. Deviation of this fine-tune causes all sorts of life-treating diseases, e.g., excessive cell growth or inadequate cell death causes diseases like cancers, autoimmune diseases, inflammatory diseases, and even viral infections. On the other hand excessive cell death or lack of cell growth can lead to neurodegenerative diseases, hematologic diseases, and tissue damage. The progression of HIV is directly linked to excess and unregulated apoptosis. Key players of this fine-tuned orchestra are growth and death factors and signaling components of the pathways mediated by them. My research interest has been related to growth and death factor-mediated signaling in cells specifically in cancer cells. We believe a lot of new molecular targets of therapeutic and diagnostic value could be revealed by understanding growth and death factor-mediated pathways.

Notable Publications

  • Monzur Rahman, Janet G. Pumphrey, and Stanley Lipkowitz. The TRAIL to targeted therapy of breast cancer. Adv Cancer Res. 2009; 103:43-73
  • Rahman L, Voeller D, Rahman M, Lipkowitz S, Allegra C, Kaye FJ, and M. Zajac-Kaye. Thymidylate Synthase as an oncogene: a novel role for an essential DNA synthesis enzyme. 2004 Cancer Cell; 5:341-351
  • Suzuki Y., M. Rahman, and H. Mitsuya. Diverse Transcriptional Response of CD4+ T Cells to Stromal Cell-Derived Factor (SDF)-1: Cell Survival Promotion and Priming Effects of SDF-1 on CD4+ T Cells. 2001. J. Immunol. 167(6):3064-73.

Patents

  • Takashi, E., Matsuyama, K. Rahman, M. Antibodies for detecting microorganism. USP Application US 20090269789Al
  • Rahman, M., Takashi, E. Antibody for detecting Chlamydia pneumoniae. Japanese patent no. 2000-62685, International publication no. WO 01-57089, TW 90101940 Canadian patent no. CA2398467 A1 2001/08/09;
  • Rahman, M., Takashi, E. for detecting Mycoplasma pneumoniae. Canadian patent no. CA2398469 A1 2001/08/09; Japanese patent no. 2000-62684. International publication no. WO 01-57199, TW 90101939
  • Rahman, M., Takashi, E. Antibody for detecting Chlamydia trachomatis. Japanese patent no. 2000-62729

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